{
  "_id": "6a37a4833efcd9bda44215a5",
  "Package": "mvmeta",
  "Type": "Package",
  "Title": "Multivariate and Univariate Meta-Analysis and Meta-Regression",
  "Version": "1.0.3",
  "Date": "2019-12-10",
  "Author": "Antonio Gasparrini",
  "Maintainer": "Antonio Gasparrini <antonio.gasparrini@lshtm.ac.uk>",
  "Description": "Collection of functions to perform fixed and\nrandom-effects multivariate and univariate meta-analysis and\nmeta-regression.",
  "URL": "http://www.ag-myresearch.com/package-mvmeta",
  "License": "GPL (>= 2)",
  "LazyData": "yes",
  "Repository": "https://gasparrini.r-universe.dev",
  "Date/Publication": "2019-12-10 11:25:03 UTC",
  "RemoteUrl": "https://github.com/gasparrini/mvmeta",
  "RemoteRef": "HEAD",
  "RemoteSha": "01c767ae87854873a4b762c2d7a270cba1ad0118",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-06-21 08:42:05 UTC",
    "User": "root"
  },
  "MD5sum": "6f093fca8846a93f2336e903039e2356",
  "_user": "gasparrini",
  "_type": "src",
  "_file": "mvmeta_1.0.3.tar.gz",
  "_fileid": "86299a661a5a6246dc249bbbc8b898dedbd8c2c24f09ed2dbbb6ef803dec8f77",
  "_filesize": 438848,
  "_sha256": "86299a661a5a6246dc249bbbc8b898dedbd8c2c24f09ed2dbbb6ef803dec8f77",
  "_created": "2026-06-21T08:42:05.000Z",
  "_published": "2026-06-21T08:44:51.330Z",
  "_distro": "noble",
  "_jobs": [
    {
      "job": 82555719566,
      "time": 136,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "7773579161"
    },
    {
      "job": 82555719559,
      "time": 126,
      "config": "linux-release-x86_64",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7773578066"
    },
    {
      "job": 82555719569,
      "time": 91,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "7773573863"
    },
    {
      "job": 82555719563,
      "time": 91,
      "config": "macos-release-arm64",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7773573816"
    },
    {
      "job": 82555542738,
      "time": 158,
      "config": "source",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7773561968"
    },
    {
      "job": 82555719556,
      "time": 104,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7773575421"
    },
    {
      "job": 82555719570,
      "time": 93,
      "config": "windows-devel",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "7773573989"
    },
    {
      "job": 82555719576,
      "time": 106,
      "config": "windows-oldrel",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "7773575705"
    },
    {
      "job": 82555719568,
      "time": 84,
      "config": "windows-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7773572977"
    }
  ],
  "_buildurl": "https://github.com/r-universe/gasparrini/actions/runs/27898924241",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_upstream": "https://github.com/gasparrini/mvmeta",
  "_commit": {
    "id": "01c767ae87854873a4b762c2d7a270cba1ad0118",
    "author": "Antonio Gasparrini <emsuagas@lshtm.ac.uk>",
    "committer": "Antonio Gasparrini <emsuagas@lshtm.ac.uk>",
    "message": "Export mixmeta functions\n",
    "time": 1575977103
  },
  "_maintainer": {
    "name": "Antonio Gasparrini",
    "email": "antonio.gasparrini@lshtm.ac.uk",
    "login": "gasparrini",
    "linkedin": "in/antonio-gasparrini-48821530",
    "description": "",
    "uuid": 13588250
  },
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 2.13.0",
      "role": "Depends"
    },
    {
      "package": "mixmeta",
      "role": "Imports"
    },
    {
      "package": "stats",
      "role": "Imports"
    },
    {
      "package": "graphics",
      "role": "Imports"
    },
    {
      "package": "grDevices",
      "role": "Imports"
    },
    {
      "package": "utils",
      "role": "Imports"
    },
    {
      "package": "metafor",
      "role": "Suggests"
    },
    {
      "package": "meta",
      "role": "Suggests"
    },
    {
      "package": "rmeta",
      "role": "Suggests"
    },
    {
      "package": "nlme",
      "role": "Suggests"
    },
    {
      "package": "MASS",
      "role": "Suggests"
    },
    {
      "package": "dlnm",
      "role": "Suggests"
    }
  ],
  "_owner": "gasparrini",
  "_selfowned": true,
  "_usedby": 9,
  "_updates": [],
  "_tags": [],
  "_stars": 7,
  "_userbio": {
    "uuid": 13588250,
    "type": "user",
    "name": "Antonio Gasparrini",
    "followers": 364
  },
  "_downloads": {
    "count": 4886,
    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/mvmeta"
  },
  "_mentions": 112,
  "_devurl": "https://github.com/gasparrini/mvmeta",
  "_searchresults": 158,
  "_rbuild": "4.6.0",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/mvmeta.html",
    "extra/NEWS.html",
    "extra/NEWS.txt",
    "extra/readme.html",
    "extra/readme.md",
    "manual.pdf"
  ],
  "_homeurl": "https://github.com/gasparrini/mvmeta",
  "_realowner": "gasparrini",
  "_cranurl": true,
  "_releases": [
    {
      "version": "0.1.0",
      "date": "2011-05-09"
    },
    {
      "version": "0.2.0",
      "date": "2011-05-10"
    },
    {
      "version": "0.2.1",
      "date": "2011-05-16"
    },
    {
      "version": "0.2.2",
      "date": "2011-06-27"
    },
    {
      "version": "0.2.3",
      "date": "2011-06-28"
    },
    {
      "version": "0.2.4",
      "date": "2012-01-10"
    },
    {
      "version": "0.3.0",
      "date": "2012-08-01"
    },
    {
      "version": "0.3.1",
      "date": "2012-08-24"
    },
    {
      "version": "0.3.4",
      "date": "2013-01-23"
    },
    {
      "version": "0.3.5",
      "date": "2013-12-11"
    },
    {
      "version": "0.4.2",
      "date": "2014-03-31"
    },
    {
      "version": "0.4.3",
      "date": "2014-04-08"
    },
    {
      "version": "0.4.4",
      "date": "2014-07-18"
    },
    {
      "version": "0.4.5",
      "date": "2014-08-09"
    },
    {
      "version": "0.4.7",
      "date": "2015-05-22"
    },
    {
      "version": "0.4.11",
      "date": "2018-03-07"
    },
    {
      "version": "1.0.2",
      "date": "2019-12-10"
    },
    {
      "version": "1.0.3",
      "date": "2019-12-10"
    }
  ],
  "_exports": [
    "blup",
    "blup.mvmeta",
    "coef.mvmeta",
    "inputcov",
    "inputna",
    "logLik.mvmeta",
    "model.frame.mvmeta",
    "model.matrix.mvmeta",
    "mvmeta",
    "mvmeta.control",
    "mvmeta.fit",
    "mvmeta.fixed",
    "mvmeta.ml",
    "mvmeta.mm",
    "mvmeta.reml",
    "mvmeta.vc",
    "mvmetaSim",
    "na.exclude.data.frame.mvmeta",
    "na.omit.data.frame.mvmeta",
    "predict.mvmeta",
    "print.mvmeta",
    "print.qtest.mvmeta",
    "print.summary.mvmeta",
    "qtest",
    "qtest.mvmeta",
    "simulate.mvmeta",
    "summary.mvmeta",
    "vcov.mvmeta",
    "vechMat",
    "xpndMat"
  ],
  "_datasets": [
    {
      "name": "berkey98",
      "title": "Five Published Trials on Periodontal Disease",
      "object": "berkey98",
      "class": [
        "data.frame"
      ],
      "fields": [
        "pubyear",
        "npat",
        "PD",
        "AL",
        "var_PD",
        "cov_PD_AL",
        "var_AL"
      ],
      "rows": 5,
      "table": true,
      "tojson": true
    },
    {
      "name": "fibrinogen",
      "title": "Fibrinogen Studies Collaboration",
      "object": "fibrinogen",
      "class": [
        "data.frame"
      ],
      "fields": [
        "cohort",
        "b2",
        "b3",
        "b4",
        "b5",
        "V_2_2",
        "V_2_3",
        "V_2_4",
        "V_2_5",
        "V_3_3",
        "V_3_4",
        "V_3_5",
        "V_4_4",
        "V_4_5",
        "V_5_5"
      ],
      "rows": 31,
      "table": true,
      "tojson": true
    },
    {
      "name": "hsls",
      "title": "High School Longitudinal Study",
      "object": "hsls",
      "class": [
        "data.frame"
      ],
      "fields": [
        "race",
        "b1",
        "b2",
        "b3",
        "V11",
        "V12",
        "V13",
        "V22",
        "V23",
        "V33"
      ],
      "rows": 8,
      "table": true,
      "tojson": true
    },
    {
      "name": "hyp",
      "title": "Ten Studies Assessing an Hypertension Treatment",
      "object": "hyp",
      "class": [
        "data.frame"
      ],
      "fields": [
        "study",
        "sbp",
        "sbp_se",
        "dbp",
        "dbp_se",
        "rho",
        "ish"
      ],
      "rows": 10,
      "table": true,
      "tojson": true
    },
    {
      "name": "p53",
      "title": "Mutant p53 Gene and Squamous Cell Carcinoma",
      "object": "p53",
      "class": [
        "data.frame"
      ],
      "fields": [
        "study",
        "y1",
        "y2",
        "V1",
        "V2"
      ],
      "rows": 6,
      "table": true,
      "tojson": true
    },
    {
      "name": "smoking",
      "title": "Meta-Analysis of Interventions to Promote Smoking Cessation",
      "object": "smoking",
      "class": [
        "data.frame"
      ],
      "fields": [
        "study",
        "design",
        "dA",
        "nA",
        "dB",
        "nB",
        "dC",
        "nC",
        "dD",
        "nD",
        "yB",
        "yC",
        "yD",
        "SBB",
        "SBC",
        "SBD",
        "SCC",
        "SCD",
        "SDD"
      ],
      "rows": 24,
      "table": true,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "mvmeta-package",
      "title": "Multivariate and Univariate Meta-Analysis and Meta-Regression",
      "topics": [
        "mvmeta-package"
      ]
    },
    {
      "page": "berkey98",
      "title": "Five Published Trials on Periodontal Disease",
      "topics": [
        "berkey98"
      ]
    },
    {
      "page": "blup",
      "title": "Best Linear Unbiased Predictions",
      "topics": [
        "blup"
      ]
    },
    {
      "page": "blup.mvmeta",
      "title": "Best Linear Unbiased Predictions from mvmeta Models",
      "topics": [
        "blup.mvmeta"
      ]
    },
    {
      "page": "coef.mvmeta",
      "title": "Extract Coefficients and (Co)Variance Matrix from mvmeta Objects",
      "topics": [
        "coef.mvmeta",
        "vcov.mvmeta"
      ]
    },
    {
      "page": "fibrinogen",
      "title": "Fibrinogen Studies Collaboration",
      "topics": [
        "fibrinogen"
      ]
    },
    {
      "page": "hsls",
      "title": "High School Longitudinal Study",
      "topics": [
        "hsls"
      ]
    },
    {
      "page": "hyp",
      "title": "Ten Studies Assessing an Hypertension Treatment",
      "topics": [
        "hyp"
      ]
    },
    {
      "page": "inputcov",
      "title": "Input (Co)Variance Matrices",
      "topics": [
        "inputcov"
      ]
    },
    {
      "page": "inputna",
      "title": "Input Missing Values",
      "topics": [
        "inputna"
      ]
    },
    {
      "page": "logLik.mvmeta",
      "title": "Extract Log-Likelihood from mvmeta Objects",
      "topics": [
        "logLik.mvmeta"
      ]
    },
    {
      "page": "mlprof.fn",
      "title": "Likelihood Functions for mvmeta Models",
      "topics": [
        "iter.igls",
        "mlprof.fn",
        "mlprof.gr",
        "remlprof.fn",
        "remlprof.gr"
      ]
    },
    {
      "page": "model.frame.mvmeta",
      "title": "Extract Model Frame and Design Matrix from mvmeta Objects",
      "topics": [
        "model.frame.mvmeta",
        "model.matrix.mvmeta"
      ]
    },
    {
      "page": "mvmeta",
      "title": "Fitting Multivariate and Univariate Meta-Analysis and Meta-Regression Models",
      "topics": [
        "mvmeta",
        "mvmeta.fit"
      ]
    },
    {
      "page": "mvmeta.control",
      "title": "Ancillary Parameters for Controlling the Fit in mvmeta Models",
      "topics": [
        "mvmeta.control"
      ]
    },
    {
      "page": "mvmeta.fixed",
      "title": "Fixed-Effects Estimator for mvmeta Models",
      "topics": [
        "mvmeta.fixed"
      ]
    },
    {
      "page": "mvmeta.ml",
      "title": "ML and REML Estimators for mvmeta Models",
      "topics": [
        "mvmeta.ml",
        "mvmeta.reml"
      ]
    },
    {
      "page": "mvmeta.mm",
      "title": "Method of Moments Estimator for mvmeta Models",
      "topics": [
        "mvmeta.mm"
      ]
    },
    {
      "page": "mvmeta.vc",
      "title": "Variance Components Estimator for mvmeta Models",
      "topics": [
        "mvmeta.vc"
      ]
    },
    {
      "page": "mvmetaCovStruct",
      "title": "Covariance Structures for mvmeta Models",
      "topics": [
        "mvmetaCovStruct"
      ]
    },
    {
      "page": "mvmetaObject",
      "title": "mvmeta Objects",
      "topics": [
        "mvmetaObject"
      ]
    },
    {
      "page": "mvmetaSim",
      "title": "Simulating Responses for mvmeta Models",
      "topics": [
        "mvmetaSim",
        "simulate.mvmeta"
      ]
    },
    {
      "page": "na.omit.data.frame.mvmeta",
      "title": "Handling Missing Values in mvmeta Models",
      "topics": [
        "na.exclude.data.frame.mvmeta",
        "na.omit.data.frame.mvmeta"
      ]
    },
    {
      "page": "p53",
      "title": "Mutant p53 Gene and Squamous Cell Carcinoma",
      "topics": [
        "p53"
      ]
    },
    {
      "page": "predict.mvmeta",
      "title": "Predicted Values from mvmeta Models",
      "topics": [
        "predict.mvmeta"
      ]
    },
    {
      "page": "qtest",
      "title": "Cochran Q Test of Heterogeneity",
      "topics": [
        "qtest"
      ]
    },
    {
      "page": "qtest.mvmeta",
      "title": "Cochran Q Test of Heterogeneity for mvmeta Models",
      "topics": [
        "print.qtest.mvmeta",
        "qtest.mvmeta"
      ]
    },
    {
      "page": "smoking",
      "title": "Meta-Analysis of Interventions to Promote Smoking Cessation",
      "topics": [
        "smoking"
      ]
    },
    {
      "page": "summary.mvmeta",
      "title": "Summarizing mvmeta Models",
      "topics": [
        "print.mvmeta",
        "print.summary.mvmeta",
        "summary.mvmeta"
      ]
    },
    {
      "page": "vechMat",
      "title": "Vectorization and Expansion of Symmetric Matrices",
      "topics": [
        "vechMat",
        "xpndMat"
      ]
    }
  ],
  "_readme": "https://github.com/gasparrini/mvmeta/raw/HEAD/README.md",
  "_rundeps": [
    "mixmeta"
  ],
  "_score": 7.8630423581011035,
  "_indexed": true,
  "_nocasepkg": "mvmeta",
  "_universes": [
    "gasparrini"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.0.3",
      "date": "2026-06-21T08:44:15.000Z",
      "distro": "noble",
      "commit": "01c767ae87854873a4b762c2d7a270cba1ad0118",
      "fileid": "93edd7be68f94eb1ab203ab232f8a91b0ee465b45f3c793e0bea9e7d21d4a938",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/gasparrini/actions/runs/27898924241"
    },
    {
      "r": "4.6.0",
      "os": "linux",
      "version": "1.0.3",
      "date": "2026-06-21T08:44:09.000Z",
      "distro": "noble",
      "commit": "01c767ae87854873a4b762c2d7a270cba1ad0118",
      "fileid": "bab165d67e3bf351373618183a93bf2b0f83e90783d985f5463eaf77562e7e72",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/gasparrini/actions/runs/27898924241"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.0.3",
      "date": "2026-06-21T08:43:36.000Z",
      "commit": "01c767ae87854873a4b762c2d7a270cba1ad0118",
      "fileid": "2c3c14c3d8eb9cdbb1ca3bf01d139dca93818d98e6ed5150c2d5263e9768fc04",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/gasparrini/actions/runs/27898924241"
    },
    {
      "r": "4.6.0",
      "os": "mac",
      "version": "1.0.3",
      "date": "2026-06-21T08:43:40.000Z",
      "commit": "01c767ae87854873a4b762c2d7a270cba1ad0118",
      "fileid": "c5e955618f6405368f35b0888cb70a6b9a5ebcbe6c869087c30eab89527f2b7d",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/gasparrini/actions/runs/27898924241"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "1.0.3",
      "date": "2026-06-21T08:44:06.000Z",
      "commit": "01c767ae87854873a4b762c2d7a270cba1ad0118",
      "fileid": "88e402cb34980f4f229e1e0c995020340e5e9d7ddc75cfa0f6d72357c0b85241",
      "status": "success",
      "buildurl": "https://github.com/r-universe/gasparrini/actions/runs/27898924241"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.0.3",
      "date": "2026-06-21T08:43:27.000Z",
      "commit": "01c767ae87854873a4b762c2d7a270cba1ad0118",
      "fileid": "ebc2be1b6bd51681d1bf26e2639d5890b8c1fb0adeee8a248f8fa8b4920c143a",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/gasparrini/actions/runs/27898924241"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "1.0.3",
      "date": "2026-06-21T08:43:45.000Z",
      "commit": "01c767ae87854873a4b762c2d7a270cba1ad0118",
      "fileid": "c286ee70227529f9ded970f582eb9089db98e8abbd3eb8b522a98be2b4b1fbbf",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/gasparrini/actions/runs/27898924241"
    },
    {
      "r": "4.6.0",
      "os": "win",
      "version": "1.0.3",
      "date": "2026-06-21T08:43:21.000Z",
      "commit": "01c767ae87854873a4b762c2d7a270cba1ad0118",
      "fileid": "93de09b1c2a58fa58bd8eda001e54b894114dfa6dde6bca862ab636a8808b122",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/gasparrini/actions/runs/27898924241"
    }
  ]
}